ZMUni Compliance Centre

Since its launch in March, our Approval Updates on China NCI newsletter has published 30 issues. We hope these updates have offered readers practical insights and a clearer view of China's cosmetic ingredient landscape. Thank you for your interest and support throughout the year. We look forward to bringing you more timely and insightful content in 2026. Wishing you a happy and healthy New Year!    From December 24 to 31, 2025, 5 new cosmetic ingredients (NCIs) have completed notifications with China's National Medical Products Administration (NMPA).       The technical requirements for the 5 NCIs mentioned above have not been disclosed, and they have not yet entered the

  On December 26, 2025, China's National Medical Products Administration (NMPA) released the draft revision of the Provisions for Management of New Cosmetic Ingredient Registration and Notification Dossiers for public consultation. The consultation period runs from December 26, 2025, to January 25, 2026, and feedback can be submitted via email to hzpjgyc@nmpa.gov.cn.   The Provisions for Management of New Cosmetic Ingredient Registration and Notification Dossiers, in effect since May 1, 2021, provide key guidance for the registration and notification of new cosmetic ingredients in China. Before their implementation, approved new ingredients were very limited, and some internationally widely used ingredients could

From December 17 to 23, 2025, 4 new cosmetic ingredients (NCIs) have completed notifications with China’s National Medical Products Administration (NMPA).   The technical requirements for the 4 new cosmetic ingredients mentioned above have not been disclosed, and they have not yet entered the safety monitoring period.      Notification No. 20250161 In March 2024, OSM filed a patent (CN 117625405 A) covering a novel Antarctic-derived Aureobasidium pullulans strain designed for pearl co-fermentation. The resulting fermentation products show enhanced UV protection, collagen promotion, skin repair, and skin barrier–strengthening effects.   Deqing OSM established in 2003, is a subsidiary of OSM Biotech Co., Ltd. Founded in 1967, OSM Biotech

  On December 19, 2025, China's National Institutes for Food and Drug Control (NIFDC) released Technical Guidelines for Cosmetic Ingredient Intended Uses(Trial), the Guidelines will come into effect on June 19, 2026.    The NIFDC also provided responses to several key questions regarding the Guidelines:   What is meant by "cosmetic ingredient intended uses"? The "intended uses" of a cosmetic ingredient refers to the intended function of the ingredient when added to a cosmetic product. This includes effects exerted at the site of application (e.g., hair dyes), as well as functions within the formulation system itself (e.g., solvents). Depending on how an

Nicotinamide mononucleotide (NMN) has long attracted global attention as a promising ingredient in health supplements and functional foods, due to its potential role in supporting cellular metabolism, healthy aging, and overall well-being.   In recent weeks, key regulatory developments driving in major markets have brought clarity to NMN's legal status, creating new opportunities for the supplement industry.      United States: FDA Restores NMN's Dietary Supplement Status   On December 9, 2025, the U.S. Food and Drug Administration (FDA) published a response letter on Regulations.gov, addressing submissions by Chinese company SyncoZymes (Shanghai) Co., Ltd. regarding β-nicotinamide mononucleotide (NMN).    *Image source: Regulations.gov   The

On December 15, 2025, according to China's National Medical Products Administration (NMPA), Nabsolute Co., Ltd. completed the notification of its first new cosmetic ingredient (NCI) in China under NCI number “国妆原备字20250159”. The ingredient, Hyaluronic Acid/Polyisopropylacrylamide Copolymer, is notable as the first NCI from Thailand to be approved in China.    *image source: China NMPA   We are honored to have partnered with Nabsolute on this project. Leveraging our professional end-to-end services—including preliminary feasibility analysis, advising on potential application scenarios for the new ingredient, and guidance on documentation preparation—we supported the company throughout the successful completion of the entire notification process. We

The global online cosmetics market is estimated at USD 22.02 billion in 2025 and is expected to reach USD 30.81 billion by 2030, growing at a CAGR of 6.95%. Asia-Pacific is the fastest-growing region, while North America remains the largest market. Most online sales occur through third-party retailer platforms (95% in 2024), though company-owned platforms are also expanding. This growth is fueled by personalization, virtual try-ons, convenience, social media influence, and rising demand for premium and organic products.   Given this rapid expansion, understanding and navigating the regulatory landscape is crucial for brands seeking to sell cosmetics internationally. This article provides a

   On December 16, 2025, China's National Institutes for Food and Drug Control (NIFDC) released two cosmetic technical guidance documents, including the Technical Guidelines for Anti-Hair Loss Products (Trial) and Technical Guidelines for Research on Efficacy-Related Ingredients in Anti-Hair Loss Cosmetics (Trial), together with the corresponding Q&A. The draft versions of these documents were previously released for public consultation in September 2025.   Key Highlights from the Q&A:   Q1: What ingredients are considered efficacy-related ingredients for anti-hair loss cosmetics? A: Efficacy-related ingredients for anti-hair loss cosmetics are divided into two categories: Anti-hair loss agents, which are single ingredients or components within ingredients