From September 11 to 17, 2025, 5 new cosmetic ingredients were notified with the China National Medical Products Administration (NMPA).
The technical requirements for the 5 new cosmetic ingredients mentioned above have not been disclosed, and they have not yet entered the safety monitoring period.
Filaggrin is a key protein involved in keratinocyte differentiation and the function of the epidermal barrier. It can be degraded into free amino acids, which, along with their derivatives—such as urocanic acid and pyrrolidone carboxylic acid—combine with other humectants to form the natural moisturizing factor, supporting hydration of the stratum corneum.
Pleione bulbocodioides is a semi-epiphytic herb belonging to the Orchidaceae family and the genus Pleione. It is a nationally protected, second-level plant in China and an endemic species. The species holds significant horticultural and medicinal value.
The notifier, Yunnan Botanee Bio-Technology Group Co., Ltd., established in 2010, is a leading player in China's health industry and the parent company of WINONA, a well-known skincare brand specializing in sensitive skin.
*Source:WINONA BEAUTY
Through its YUNKE Characteristic Plant Lab and leveraging the rich botanical resources of Yunnan province, Botanee is dedicated to researching the unique properties of native plants and highlighting the natural beauty of China's biodiversity. As of September 17, 2025, the company has notified 17 new cosmetic ingredients, all derived from botanical sources.
Bakuchiol is obtained by crushing Psoralea corylifolia seeds, followed by extraction, purification, and removal of impurities and solvents to yield a high-purity product. It is an organic compound with reported functions as an antimicrobial, antioxidant, emollient, and skin-conditioning agent.
In August 2022, the first Bakuchiol(Notification 20220027) was officially notified as an NCI with the China NMPA. To date, there are seven notified entries, one of which has been canceled, while five have entered the safety monitoring period. This indicates that bakuchiol has already been used in products and highlights the popularity of this raw material.
Gingerone A is a naturally derived compound extracted from plants, primarily from Zingiberaceae species such as ginger. Due to its unique bioactivity, this compound has attracted considerable attention in biomedical research in recent years.
Crocodile oil is rich in polyunsaturated fatty acids, amino acids, and various active compounds, with potential benefits in moisturizing, repairing, and antioxidant care. It helps support epidermal cell renewal and maintain skin vitality, contributing to hydration, wrinkle reduction, repair, brightening, and anti-aging effects. This offers cosmetics companies a natural option for developing effective skincare products and provides consumers with a unique bioactive skincare experience.
Issue 18: New Notifications Feature Ferment, Botanical, and Peptide
Issue 17: New Approvals Highlight Biotech-derived Actives and Botanicals
Issue 16: Diverse Approvals in Peptides, Botanicals, Ferments, and Compounds
Issue 15: Continued Interest in Biotech and Botanical Ingredients
......
