From August 6 to August 13, 2025, 5 new cosmetic ingredients were notified with the China National Medical Products Administration (NMPA).
The technical requirements for the 5 new cosmetic ingredients mentioned above have not been disclosed, and they have not yet entered the safety monitoring period.
6'-SL is an important member of the human milk oligosaccharides (HMOs) family, composed of galactose, glucose, and sialic acid. As one of the most abundant sialylated HMOs in breast milk, 6'-SL is known for its exceptional moisturizing and skin-repairing properties.
Previously, 6'-SL obtained approval for use in food applications from both the U.S. FDA (GRAS status) and the European EFSA (Novel Food approval). In China, 6'-SL has been submitted multiple times to the National Health Commission (NHC) for approval as a new food additive. Now, 6'-SL completed NCI notification ahead of its approval as a “Three New Food” in China, making it the sixth HMO-related ingredient to be notified in NCI system. Of these six approved HMOs, five—including the newly notified 6'-SL—were submitted with the assistance of ZMUni.
Hexapeptide-117 is a synthetic peptide composed of alanine, glutamic acid, leucine, proline, and valine. In addition, several Hexapeptide-related ingredients have already been included in the Inventory of Existing Cosmetic Ingredients in China (IECIC) List I.
*Source: China NMPA
Paeonia Emodi, known as Himalayan peony in English and 多花芍药 (meaning "multi-flower peony") in Chinese, is a species in the genus Paeonia of the family Paeoniaceae. It is usually found in India, Nepal, and China's Tibet Autonomous Region, typically growing on mountain slopes at elevations around 2,350 meters. Besides, several other Paeonia-related ingredients have already been included in the IECIC List I.
*Source: China NMPA
Also, we're delighted to announce that this ingredient was submitted with the support of ZMUni, marking our 22nd successful NCI notification application this year—accounting for over 20% of all approvals in 2025.
Up to now, ZMUni Compliance Centre has supported numerous domestic and international cosmetic & ingredient companies in completing cosmetic new ingredient applications in China. Our team brings extensive hands-on experience, having managed over a hundred NCI projects covering a wide range of ingredient types, including chemical substances, botanical extracts, dual-use cosmetic-food ingredients, peptides, polymers, and more. For any related inquiries, feel free to contact us at info@zmuni.com. We're always here to help.
Previous Updates:
l Issue15: Continued Interest in Biotech and Botanical Ingredients
l Issue 14: Peptides Continue to Gain Attention
l Issue 13: Clean Beauty Brand Notifying Plant Extract
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