Regulatory Updates 归档

China's NCI Approval Updates: Ongoing Notifications by Major Chinese Players

Publication date：2026-03-04

From February 24 to March 3, 2026, 7 new cosmetic ingredients (NCIs) have completed notifications with China's National Medical Products Administration (NMPA).

Staphylococcus Epidermidis Ferment Filtrate

Staphylococcus epidermidis is a commensal bacterium naturally found on human skin. Often referred to as a "sentinel bacterium," it plays an important role in maintaining skin homeostasis.

Freda previously published a related study in Probiotics and Antimicrobial Proteins (DOI: 10.1007/s12602-025-10877-9). The research focused on the cell-free fermentation supernatant of Staphylococcus epidermidis CCSM0322, a strain isolated from healthy skin. Its antioxidant, anti-inflammatory, and skin barrier protective effects were evaluated using a UVB-induced HaCaT in vitro model.

The study confirmed that the fermentation filtrate of Staphylococcus epidermidis CCSM0287 effectively alleviated UVB-induced skin inflammation and oxidative damage. It may serve as a promising candidate ingredient for managing skin inflammation and photo-induced damage. In the future, it could be developed into skin-derived microbiome cosmetic ingredients to help support overall skin health.

Freda is a China-based biotechnology company engaged in the research, development, and production of cosmetic ingredients. Its portfolio includes hyaluronic acid, peptides, recombinant collagen, and microbiome-related ingredients. The company applies bio-fermentation and skin science research in the development of functional cosmetic raw materials and supplies ingredients to domestic and international markets.

Saussurea Laniceps Callus Extract

Saussurea Laniceps is a perennial, monocarpic herb belonging to the genus Saussurea in the Asteraceae family. It is endemic to China and typically grows on alpine scree at elevations of 3,200–5,280 meters. The species is distributed in Yunnan, Tibet, and Sichuan, and is currently listed as a National Class II Protected Wild Plant in China.

Linzhi Himalaya Third Pole Biotechnology Co., Ltd., established in 2018, is a subsidiary of Shanghai CHANDO Group Co., Ltd. The company focuses on research into plants, minerals, water, and microorganisms, and serves as an important R&D center within the group. To date, the company has completed the notifications of two NCIs. In addition.

CHANDO Group, founded in 2001, is a Chinese cosmetics group operating multiple skincare and personal care brands, including CHANDO, MAYSU, SpringSummer, Biorrier, and imine. The group places emphasis on product research and brand development, and has established research initiatives in Tibet through its subsidiary, focusing on high-altitude natural resources and biodiversity exploration, which has become part of its ingredient research strategy.

Acer Truncatum Seed Oil

Acer truncatum is a deciduous tree species of the genus Acer in the Sapindaceae family. It is widely distributed in China, from the Northeast and North China regions westward to Shaanxi, Sichuan, and Hubei, and southward to Zhejiang and Jiangxi provinces.

Acer truncatum seed oil, sometimes referred to as “natural brain gold,” was officially approved in March 2011 by the former Ministry of Health of China (now the National Health Commission) as a novel food ingredient. The oil is produced from the kernels of Acer truncatum seeds through pressing, decolorization, and deodorization processes. Its approved use does not include infant food.

Shanghai Pechoin Daily Chemical Co., Ltd. is a Chinese cosmetics company engaged in the research, development, production, and sale of skincare and personal care products. It operates under the Pechoin Group and manages several well-known domestic beauty brands in the Chinese market.

Pechoin, founded in 1931 in Shanghai, is one of China’s long-established skincare brands. During the Republican era, it was considered a representative domestic cosmetics brand and achieved nationwide recognition. After a period of adjustment, the brand underwent repositioning and product innovation in the 2000s, gradually rebuilding its presence in the modern Chinese beauty market.