On October 20, 2025, China's National Medical Products Administration (NMPA) has carried out the second dynamic update of the Inventory of Existing Cosmetic Ingredients in China (IECIC), following the first update earlier this year, which set the precedent for regular adjustments to ensure ingredient safety and regulatory compliance.
The updates to the inventory specifically includes:
According to relevant regulations, new cosmetic ingredients (NCIs) that have completed a three-year safety monitoring period are reviewed by technical evaluation bodies. If deemed to meet safety requirements, they are officially included in List II of the IECIC.
Following the previous inclusion of two approved NCIs, three NCIs have now been included to List II of the IECIC. All NCIs inculded in IECIC List II:
|
No. |
INCI Name |
CAS No. |
Reported Function |
Date of Inclusion(in List II) |
|
1 |
ACETYLNEURAMINIC ACID |
131-48-6 |
Humectant |
June 23, 2025 |
|
2 |
BETA-ALANYL HYDROXYPROLYLDIAMINOBUTYROYL BENZYLAMIDE |
1694678-02-8 |
Skin Protectants |
|
|
3 |
LAUROYL ALANINE |
52558-74-4 |
Cleansing |
October 20, 2025 |
|
4 |
POLYMETHYLSILSESQUIOXANE/TRIMETHYLSILOXYSILICATE |
1402155-47-8 |
Film Formers |
|
|
5 |
BIS-CETEARYL AMODIMETHICONE |
1126942-72-0 |
Hair Conditioning Agents |
List I serves as an objective compilation of cosmetic ingredients that have already been used in products manufactured or sold in China. In this latest dynamic update, 49 ingredient entries have been revised, primarily to standardize their Chinese and INCI/English names.
In addition, a new "Revision Suggestions" feature has been added to the IECIC online database, enabling companies and the public to submit feedback and recommendations. The NMPA stated it will carefully review and incorporate the collected opinions to further improve and refine the IECIC on an ongoing basis.
Query Interface:
https://www.nmpa.gov.cn/hzhp/hzhpjgdt/20251020091655117.html
