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Regulatory Updates

China's NCI Approval Updates (April 11 to 21, 2025)
Publication date:2025-04-22

 

To help overseas companies stay up to date with cosmetic ingredient trends in China, ZMUni Compliance Centre will publish a regular series on New Cosmetic Ingredient (NCI) notifications. We hope this provides valuable insights for ingredient suppliers and brands looking to enter the Chinese market.

 

 

From April 11 to 21, 2025, 2 new cosmetic ingredients were notified with the China National Medical Products Administration (NMPA). They include:

Ingredient Name in CN

Notification No.

Notifier in CN

透明质酸水杨酸酯钠

202500035

华熙生物科技股份有限公司

N-乙酰基-丝氨酰-脯氨酰-缬氨酰-异亮氨酰-缬氨酰-脯氨酰胺

202500036

北京茂思商贸有限公司

 

The technical requirements for the 2 new cosmetic ingredients mentioned above have not been disclosed, and they have not yet entered the safety monitoring period.

 

透明质酸水杨酸酯钠 (a derivative of hyaluronic acid)

This ingredient was notified by Bloomage, a prominent global biotechnology and biomaterial company that specializes in the industrialization of hyaluronic acid.

 

According to a patent filed by Bloomage, this ingredient is a derivative of hyaluronic acid—specifically, a hyaluronic acid ester synthesized from hyaluronic acid or its salts and salicylate. The hyaluronic acid ester disclosed in the application exhibits good water solubility, low irritation, mildness, and the ability to optimize the stratum corneum. The water-soluble ester form helps reduce the penetration of salicylic acid into the stratum corneum while enhancing its anti-aging effects within the stratum corneum.

 

N-乙酰基-丝氨酰-脯氨酰-缬氨酰-异亮氨酰-缬氨酰-脯氨酰胺(Peptide Ingredient)

Notification 202500036 was notified by Beijing Maosi Trading Co., LTD, the parent company of AFU (阿芙), a well-established Chinese skincare brand specializing in essential oil-based products.

 

The brand emphasizes a philosophy of "nourishing the skin with oil" and "healing through aroma," blending natural ingredients with modern skincare science to cater to consumers seeking gentle yet effective skincare solutions

 

Afu's product range includes essential oils, serums, facial masks, and toners. Notable products include the "11 Seeds Ferment Essence Toner" and the "Aurora Rose Facial Oil," both of which have received positive reviews for their moisturizing and skin-brightening properties .

 

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As of now, 36 NCIs have been successfully notified in China in 2025. ZMUni Compliance Centre is proud to have assisted with one-sixth of these notifications. We congratulate all the companies involved and look forward to seeing these innovative ingredients applied in future products.

 

With deep regulatory expertise and hands-on project experience, ZMUni continues to support global clients in navigating China's complex cosmetic ingredient application system with efficiency and success. If you're looking to register or notify NCIs in China, feel free to reach out — we're here to help.

 

 

*All product images are sourced from Tmall.