On June 24, 2025, China National Medical Products Administration (NMPA) issued an important announcement regarding significant adjustments for the Inventory of Existing Cosmetic Ingredient in China (IECIC). Detailed adjustments are as follows: 1. Introducing Two-tier Inventory System List I includes revisions and improvements to the IECIC 2021. List II covers new cosmetic ingredients that have completed their three-year safety monitoring period and are now officially included in IECIC. *Background: In accordance with the Cosmetics Supervision and Administration Regulation, cosmetic ingredients that have completed the three-year safety monitoring period after being registered or notified as new cosmetic ingredients—without any safety
