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China's NCI Approval Updates: Rice, Blueberry, HMOs, Peptides and More
Published on:2026-07-20

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From July 10 to 17, a total of eight new cosmetic ingredients completed notification with China's National Medical Products Administration (NMPA). The technical requirements for all related NCIs have not been publicly disclosed.

 

 

Plant Extracts

 

Oryza Sativa (Rice) Hull Extract (Notification No. 20260122)

This ingredient was filed by an affiliate company of the renowned beauty brand MISTINE. Oryza sativa subsp. indica (Indica rice) is a plant belonging to the genus Oryza in the Poaceae family and is mainly cultivated in tropical and subtropical regions. Previously, rice-derived ingredients such as Oryza Sativa (Rice) Extract had been filed by other companies.

 

Malus micromalus flower extract (Notification No. 20260126)

Malus micromalus (Chinese crabapple) is a plant belonging to the Rosaceae family and Malus genus, and is native to China. It is known for its adaptability to sunlight, cold, and drought conditions, with its fruits being edible and widely used in food applications.

 

The ingredient was filed by Proya Cosmetics Co., Ltd., a leading publicly listed Chinese beauty company engaged in cosmetic R&D, manufacturing, and sales. Proya owns several well-known beauty brands, including PROYA, TIMAGE, Off&Relax, HAPSODE, and CORRECTORS, covering skincare, makeup, hair care, and high-efficacy beauty products.

 

Vaccinium Corymbosum (Blueberry) Fruit Extract (Notification No. 20260129)

Vaccinium corymbosum (Highbush Blueberry) is a deciduous shrub belonging to the Ericaceae family and Vaccinium genus. Its fruits are rich in anthocyanins, vitamin C, dietary fiber, and other bioactive components. Highbush Blueberry Fruit Extract is known for its antioxidant properties and has been widely applied in dietary supplements, functional foods, cosmetics, and pharmaceutical fields.

 

 

Plant/Natural Active Ingredients

 

Amentoflavone (Notification No. 20260123)

Amentoflavone is a naturally occurring biflavonoid compound widely found in various plant species, including those from the families Selaginellaceae, Cupressaceae, Taxodiaceae, and Ginkgoaceae. It is particularly abundant in plants of the genus Selaginella. As a plant-derived bioactive compound, amentoflavone has been reported to possess antioxidant, anti-inflammatory, and other biological activities, and has attracted interest for applications in cosmetics, healthcare, and pharmaceutical fields.

 

Ginsenoside Rg1 (Notification No. 20260127)

Ginsenoside Rg1 is a tetracyclic triterpenoid compound derived from the roots of Panax ginseng (ginseng), a plant belonging to the Araliaceae family. As one of the key bioactive constituents of ginseng, ginsenoside Rg1 has attracted significant research interest due to its antioxidant, anti-aging, and skin-conditioning potential, and has been widely studied for cosmetic and healthcare applications.

  

 

Peptides / Synthetic Peptides

 

Hexapeptide-10 (Notification No. 20260125)

According to the PCPC wINCI Database, Hexapeptide-10 is classified as a "Skin-Conditioning Agent – Miscellaneous." The notifier, Winkey Technology, focuses on the R&D, manufacturing, and commercialization of cosmetic ingredients, particularly bioactive peptides and botanical ingredients derived from Chinese resources. Since 2021, Winkey Technology and its subsidiaries have filed 25 cosmetic new ingredients, with 1 ingredient included in List II of the Inventory of Existing Cosmetic Ingredients in China (IECIC) and 16 ingredients currently under the safety monitoring period.

 

Pentapeptide-130 AEEA-AEEA Tetrapeptide-150 (Notification No. 20260128)

This ingredient was filed by RéVive Skincare Laboratory Co., Ltd. (RéVive Skincare). Founded in 1997 by American plastic surgeon Dr. Gregory Bays Brown, RéVive Skincare originated from his research in burn wound healing and later incorporated EGF-inspired biotechnology into the development of advanced anti-aging skincare products. The brand is recognized as a premium efficacy-focused skincare brand. Previously, RéVive Skincare also filed another NCI, Pentapeptide-129 AEEA-AEEA Tetrapeptide-10 (Notification No. 20260040).

 

 

Fermentation / Oligosaccharides

 

Human milk oligosaccharides (HMOs) are a group of complex oligosaccharides naturally found in human breast milk. 2′-Fucosyllactose (2′-FL) is one of the major HMOs with extensive research and applications. It has been approved for use in food applications, including infant formula, by regulatory authorities and organizations such as the U.S. FDA, the European Commission, Food Standards Australia New Zealand (FSANZ), and China’s National Health Commission (NHC).

 

 

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