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China's NCI Approval Updates: 6 NCIs spanning peptides, surfactants, and botanicals
Published on:2026-04-07

 

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From April 1 to 7, 2026, 6 new cosmetic ingredients (NCIs) have completed notifications with China's National Medical Products Administration (NMPA).

 

Cyclic Peptides

 

In this issue, two of the newly notified NCIs are cyclic peptides. Compared with linear peptides, cyclic peptides demonstrate stronger resistance to enzymatic degradation and greater structural stability, thereby enhancing the longevity of skincare efficacy.

 

Among them, Notification No. 20260053 was filed by the well-known Chinese cosmetics company Proya. Notification No. 20260057, Cyclo sh-Pentapeptide-46 SP, was filed by Zhejiang Peptites Biotech Co., Ltd., a leading Chinese raw material supplier.

 

It is worth noting that Cyclo sh-Pentapeptide-46 SP was successfully supported through the compliance process with the assistance of ZMUni Compliance Center. Building on our continued collaboration with Peptites Biotech, which has already seen the successful completion of several other NCI notifications, we remain committed to supporting the compliant commercialization of the company’s innovative achievements.

 

 

Chemical Compounds

 

Among the six newly notified NCIs in this update, two are chemical ingredients, both notified by overseas companies: Notification No. 20260052 by Clariant International Ltd., and Notification No. 20260056 by AEKYUNG IND. CO., LTD. Based on the Chinese names of the notified NCIs, both compounds are expected to be used as surfactants.

 

 

Botanical Ingredient

 

Acer truncatum seed oil, sometimes referred to as "natural brain gold," was officially approved in March 2011 by the former Ministry of Health of China (now the National Health Commission) as a novel food ingredient. The oil is produced from the kernels of Acer truncatum seeds through pressing, decolorization, and deodorization processes. Its approved use does not include infant food.

 

 

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