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China's NCI Approval Updates: Featuring a Korean Microbiome-Derived Ferment
Published on:2026-04-13

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From April 10 to 12, 2026, 3 new cosmetic ingredients (NCIs) have completed notifications with China's National Medical Products Administration (NMPA).

 

 

Cyclocarya Paliurus Leaf Extract

 

Cyclocarya paliurus (Batal.) Iljinskaja, a deciduous tree species in the walnut family endemic to China, is primarily found in the middle and lower reaches of the Yangtze River. It is commonly referred to as the "money tree" due to its distinctive coin-shaped fruits.

 

In 2013, the National Health Commission of China (formerly the National Health and Family Planning Commission) officially approved its leaves as a novel food ingredient, opening the door for broader development and commercial applications.

 

Extracts from Cyclocarya paliurus leaves are rich in flavonoids, polyphenols, and triterpenes. Among these, the synergistic activity of key flavonoids—such as quercetin-3-O-β-D-glucuronide, quercetin, and kaempferol—is considered central to its functional potential, contributing to anti-wrinkle, soothing, and skin-repairing effects in cosmetic applications.

 

 

Enterococcus Faecalis Ferment

 

Enterococcus Faecalis Ferment notified by Cell Biotech, a Korea-based microbiome biotech company focused on probiotic and fermentation technologies, with applications in both dietary supplements and cosmetic ingredients.

 

This marks the ninth NCI notified by Korean companies. Among overseas applicants, Korean companies rank third in terms of the number of notified NCIs, following the United States (19) and Italy (11).

 

 

Kavain

 

Kava (Piper methysticum Forster) is a perennial medicinal shrub primarily distributed across South Pacific island regions. Modern pharmacological studies have shown that kava exhibits a range of biological activities, including anxiolytic, sedative-hypnotic, muscle relaxant, local anesthetic, as well as anti-inflammatory and antimicrobial effects, with the advantages of low dependence risk and good tolerability.

 

Kavain is one of the key bioactive compounds isolated from kava roots and is considered a major contributor to its pharmacological effects.

 

 

Previous Updates:

Issue 38: 6 NCIs spanning peptides, surfactants, and botanicals

Issue 37: Diverse Innovations Across Bioactives and Materials

Issue 36: New Natural and Bioactive Ingredients

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